All content included on our site, such as text, images, digital downloads and other, is the property of its content suppliers and protected by us and international laws. Semiparametric theory and missing data pdf free download. Values in a data set are missing completely at random mcar if the events that lead to any particular dataitem being missing are independent both of observable variables and of unobservable parameters of interest, and occur entirely at random. In this article, we consider a general rankbased estimating method for model 1. Semiparametric inverse propensity weighting for nonignorable. Nonlogit maximumlikelihood estimators are inconsistent when using data on a subset of the choices available to agents. The weights considered may not be predictable as required in a martingale stochastic process formulation. When data are mcar, the analysis performed on the data is unbiased. Semiparametric theory and missing data researchgate. Semiparametric regression for the social sciences keele. Imputation and dynamic models in semiparametric survival.
Semiparametric regression can be of substantial value in the solution of complex scienti. To remove this serious limitation on the methodology. Semiparametric theory and missing data springerlink. In particular, we investigate a class of regressionlike mean regression, quantile regression, models with missing data, an example of a supply and demand simultaneous equations model and a. Analysis of generalized semiparametric regression models. The geometric ideas for semiparametric fulldata models are extended to missingdata models. A process point of view, by aalen, borgan and gjessing. An outcome is said to be missing not at random mnar if, conditional on the observed variables, the missing data mechanism still depends on the unobserved outcome. Semiparametric theory and missing data springer series in statistics series by anastasios tsiatis. In such settings, identification is generally not possible. In this paper, we consider a semiparametric regression model in the presence of missing covariates for nonparametric components under a bayesian framework.
Missing data occur frequently in empirical studies in health and social sciences, often compromising our ability to make accurate inferences. An introductory guide to smoothing techniques, semiparametric estimators, and their related methods, this book describes the methodology via a selection of carefully explained examples and data sets. Semiparametric regression analysis with missing response. We also discuss the asymptotic properties of estimates. Semiparametric regression analysis with missing response at random qihua wang, oliver linton and wolfgang h. The theory of missing data applied to semiparametric models is scattered throughout the literature with no thorough comprehensive treatment of the subject. Imputation and dynamic models in semiparametric survival analysis by xiaohong liu. The application to missing data is also clearly of great interest. Our theoretical results provide new insight for the theory of semiparametric efficiency bounds literature and open the door to new applications. Sieve maximum likelihood estimation for a general class of accelerated hazards models with bundled parameters zhao, xingqiu, wu, yuanshan, and yin, guosheng, bernoulli, 2017. Missing data is frequently encountered in many areas of statistics.
Analysis of semiparametric regression models for repeated. This treatment will give the reader a deep understanding of the underlying theory for missing and coarsened data. Semiparametric regression models reduce complex data sets to summaries that we can understand. Statistics in the pharmaceutical industry, 3rd edition. By adopting nonparametric components for the model, the estimation method can be made robust. Semiparametric theory and missing data by anastasios tsiatis ebook summary download. The description of the theory of estimation for semiparametric models is both rigorous and intuitive, relying on geometric ideas to reinforce the intuition and understanding of the theory. We consider a class of doubly weighted rankbased estimating methods for the transformation or accelerated failure time model with missing data as arise, for example, in casecohort studies. We propose a multiple imputation estimator for parameter estimation in a quantile regression model when some covariates are missing at random. Empirical process approach in a twosample locationscale model with censored data hsieh, fushing, the annals of statistics, 1996. The theory is applied to a semiparametric missing data model where it is shown that the twostep gelweighted estimator possesses good efficiency and robustness properties when nuisance models are. Analysis of generalized semiparametric regression models for.
Assume that cause j i 1 is the primary cause of interest and j i 1 for other competing causes. Semiparametric theory and missing data by tsiatis, a. Values in a data set are missing completely at random mcar if the events that lead to any particular data item being missing are independent both of observable variables and of unobservable parameters of interest, and occur entirely at random. Generalized semiparametric model and missing data let t i be the failure time and j i. This comprehensive monograph offers an indepth look at the associated theory. Semiparametric theory for causal mediation analysis. Modelling survival data in medical research, by collett 2nd edition 2003 survival and event history analysis. We introduce below novel bounded influence function estimators. Ebook semiparametric theory and missing data springer. The following are some the books on survival analysis that i have found useful. A semiparametric inference to regression analysis with. Semiparametric theory and missing data anastasios tsiatis. In order to derive asymptotic properties for singleindex models.
Pdf analysis of semiparametric regression models for. This book combines much of what is known in regard to the theory of estimation for semiparametric models with missing data in an organized and comprehensive manner. Semiparametric estimation of multinomial discretechoice. Semiparametric methods for missing data problems and their. Missing data often appear as a practical problem while applying classical models in the statistical analysis.
Enjoy reading 388 pages by starting download or read online semiparametric theory and missing data. In many cases, the treatment of missing data in an analysis is carried out in a casual and adhoc manner, leading, in many cases, to invalid inference and erroneous conclusions. This theory is very interesting in its own right important examples of the models discussed are generalized estimating equations for multivariate data and coxs proportional hazards model for survival data. V \displaystyle \theta \subseteq \mathbb r k\times v, where v \displaystyle v is an infinitedimensional space. Semiparametric efficient empirical higher order influence. Classical semiparametric inference with missing outcome data is not robust to contamination of the observed data and a single observation can have arbitrarily large influence on estimation of a parameter of interest. A semiparametric logistic regression model is assumed for the response probability and a nonparametric regression approach for missing data discussed in cheng 1994 is used in the estimator. With a semiparametric model, the parameter has both a finitedimensional component and an infinitedimensional component often a realvalued function defined on the real line.
There are of course many other good ones not listed. Statistical analysis in the presence of missing data has been an area of considerable interest because ignoring the missing data often destroys the representativeness of the remaining sample and is likely to lead to biased parameter estimates. Parameter estimation in parametric regression models with missing coariatesv is considered under a survey sampling setup. The estimation procedure fully utilizes the entire dataset to achieve increased efficiency, and the resulting coefficient estimators are root n consistent and asymptotically normal. Methods for the analysis of sampled cohort data in the cox. Pdf semiparametric estimation with data missing not at. It also demonstrates the potential of these techniques using detailed empirical examples drawn from the social and political sciences. The ipw methods rely on the intuitive idea of creating a pseudopopulation of weighted copies of the complete cases to remove selection bias introduced by the missing data. Twostep semiparametric empirical likelihood inference. This sensitivity is exacerbated when inverse probability weighting methods are used, which may overweight contaminated observations. A semiparametric estimation of mean functionals with. The theory is applied to a semiparametric missing data model where it is shown that the twostep gelweighted estimator possesses good efficiency and.
Twostep semiparametric empirical likelihood inference 5 albeit it does also include models that can be estimated with semiparametric maximum and quasi maximum likelihood methods, for which 2. Ebook semiparametric theory and missing data springer series. It starts with the study of semiparametric methods when there are no missing data. This book summarizes current knowledge regarding the theory of estimation for semiparametric models with missing data, in an organized and comprehensive manner. Motivated by the national morbidity, mortality and air pollution study, we propose a semiparametric functional single index model to study the relation between a univariate response and multiple functional covariates. Stat992bmi826 universityofwisconsinmadison missing data. Download semiparametric theory and missing data free pdf ebook online. Semiparametric estimation of multinomial discretechoice models using a subset of choices jeremy t. On weighting approaches for missing data lingling li. Methods for estimating parameters with missing or coarsened data in as e. A semiparametric inference to regression analysis with missing coariatesv in survey data shu angy and jae kwang kim department of statistics, iowa state university abstract. A semiparametric model for heterogeneous panel data with fixed e ects lena k orber the london school of economics oliver lintonyand michael vogtz university of cambridge january 18, 20 this paper develops methodology for semiparametric panel data models in a setting where both the time series and the cross section are large. Pdf a functional single index model semantic scholar.
Semiparametric modelling is, as its name suggests, a hybrid of the parametric and nonparametric approaches to construction, fitting, and validation of statistical models. Empirical likelihood semiparametric nonlinear regression. Theory and practice by qi li in doc, epub, txt download ebook. I show that the semiparametric, multinomial maximumscore estimator is consistent when using data on a subset of choices. The parametric part of the model integrates the functional linear regression model and the sufficient dimension reduction structure. A semiparametric model for heterogeneous panel data with. The first part of the book describes the theory for estimation in semiparametric models in the absence of missing data. Semiparametric inference with missing outcome data including causal inference is based on partially specified models which are not of direct interest e.
Abstract we develop inference tools in a semiparametric partially linear regression model with missing response data. Marginal structural models for the estimation of direct and indirect effects. To remove this serious limitation on the methodology, we. We consider a class of doubly weighted rankbased estimating methods for the transformation or accelerated failure time model with missing data as arise, for.
These methods are then applied to problems with missing, censored, and coarsened data with the goal of deriving estimators that are as robust and efficient. Analysis of semiparametric regression models for repeated outcomes in the presence of missing data james m. Robins, andrea rotnitzky, and lue ping zhao we propose a class of inverse probability of censoring weighted estimators for the parameters of models for the dependence of the. For semiparametric methods using the generalized estimating functions liang and zeger, 1986, as another class of examples, if data are missing at random and the missing propensity function is. Semiparametric theory and missing data book summary. Strategies for bayesian modeling and sensitivity analysis m.
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